{"product_id":"sunbright-me-2m200bd-np","title":"SUNBRIGHT® ME-2M200BD-NP","description":"\u003cp\u003e\u003cspan style=\"color: #333300;\"\u003eSUNBRIGHT ME-2M200BD-NP is a novel acetal linkage releasable PEG with a self-immolative linker structure, designed to release native bioactive substances under physiological conditions. It consists of a 20 kDa PEG chain conjugated to a cleavable aromatic acetal unit, enabling gradual release through hydrolysis.\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #333300;\"\u003eThe release rate of the bioactive substance can be finely tuned by modifying the substituent on the aromatic ring. In vitro studies demonstrated that ME-2M200BD-NP exhibited a half-life of approximately 2.7 days at pH 7.4, allowing controlled release kinetics suitable for protein and peptide conjugation. \u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #333300;\"\u003eME-2M200BD-NP is a useful material for advanced drug delivery, enhancing the blood stability of bioactive substances and achieving prolonged bioactivity by gradually releasing the native bioactive substance into the bloodstream.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #333300;\"\u003ea-{3-methoxy-4-[6-methyl-8-({[(4-nitrophenoxy)carbonyl]oxy}methyl)-4H-benzo[d][1,3]dioxin-2-yl]phenyl}-w-methoxy, poly(oxyethylene)\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan style=\"color: #333300;\"\u003eIn vitro half-life (pH7.4) 2.7d\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e","brand":"NOF AMERICA","offers":[{"title":"100mg amber glass bottle","offer_id":54966333505760,"sku":"ejj1789665979979","price":127.05,"currency_code":"USD","in_stock":true},{"title":"1g amber glass bottle","offer_id":54966333538528,"sku":"tms1789665979980","price":508.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0810\/5613\/7440\/files\/sunbright-me-2m200bd-np_1.jpg?v=1789665983","url":"https:\/\/yogabalanceclad.shop\/products\/sunbright-me-2m200bd-np","provider":"My Store","version":"1.0","type":"link"}